Copying DNA is our key Technology

We revoluTionize vaccine developmenT

We hunT down paThogens

We look for new colleagues

Ready for big Things?


Time is a crucial issue in vaccine development. In order to save as many lives as possible, we want to realize a faster process for finding vaccine candidates, preferably reducing the time needed therefor from months to merely '48 hours'.

With our patented biomolecule copier, we are able to copy DNA of pathogens (e.g. virus, bacteria) in to a microarray. In a second copying step, taking place in a microfluidic chamber, we convert the DNA into a protein microarray, which displays all pathogen proteins. Subsequently, we add a drop of blood from a survivor of the given disease. Naturally, the survivor’s blood contains high amounts of protecting antibodies against the pathogen. Thus, these antibodies will bind to all proteins enabling immunity. Such proteins are potential vaccine candidates – found within '48 hours'.

We bring the vaccine candidate finding process to a new level, with faster analysis and higher coverage making us all prepared for the next outbreaks after Ebola (2015) and Zika (2016).


CorporaTe CulTure

Core values are part of a company’s DNA. They should be self-evident and within one's own heart and mind.


[in-teg-ri-tee] derives from the old Latin word "integritas" and even at that time it basically meant – to be whole - and as such authentic, to follow a righteous path of honesty, truthfulness and accuracy and having strong moral principles.

Integrity is the essence for being a trustworthy and responsible partner, employer, employee, colleague and customer. It is not always easy to follow this inner sense of wholeness and rightness, but we will not compromise these values for higher profits or to strengthen our market position. Therefore, at the end of the day, we can look into the mirror and wear a contented smile - knowing that we are still whole and hoping to be on the right way - for us and all others.


A fulfilling workplace to come to each day, one that excites employees, inspires them in creativity and offers them growth and development is the foundation of a pleasant and creative atmosphere. We embrace diversity and personal development, recognize and reward individual contributions to corporate values and achievements.

Employees benefit amongst others from inspiring working spaces, free drinks, food, snacks, flexible and family-friendly working arrangements. When you come and leave with a smile every day, we did it right.


We welcome mavericks, entrepreneurial mindsets, risk takers, change makers, tinkerers and everyone with passion, who does not seek a job but a calling. Combined with mindful leadership we encourage our team members to bring all their talents to work and to become truly engaged co-creators on our journey.

Conscious Capitalism

We believe that long term success can only be reached if a company’s performance is in balance with benefits for humans and the environment. A conscious business model is based on a triple bottom line combining the values people, planet and profit.

BioCopy, for instance, introduces stock shares for employees to provide them with special appreciation, rewards for suggestions to save resources and environment-friendly mobility. As a purpose-driven company we want to have a long-lasting impact and leave a legacy.


We are committed to excellence and high quality and support activities enhancing the intellectual and social competence of employees. This includes international conferences, internships to partners, team building events, lectures, personal and professional workshops. We are thriving for cutting edge technologies and breakthrough innovations. Our hierarchies are built on competence, not on title.

Team Spirit

BioCopy consists of a diverse team of different genders and education - engineers, biologists, physicists and businessmen. We promote an open and free exchange of views and ideas. Acting beyond one’s own scope of responsibilities as well as inspiring others to succeed and develop is appreciated.

A key component is to create an environment where teamwork can flourish through open, honest, regular and prompt communication. If you like to explore the end of the world with us, you are at the right place.


Dr. Günter Roth

CEO & Founder

Main inventor and sword fighter

Christin Rath

CSO & Founder

Lab leader and fitness junkie

Niko Bausch

CFO & Founder

Finance / internal operations and outdoor freak

Jürgen Burger

CTO & Founder

Mechatronical engineer infected by biotech virus

Normann Kilb

Scientific R&D

Has a passion for proteins – in the lab & kitchen

Tobias Herz

Scientific R&D

Copies proteins and likes Crossfit

Stefan Krämer

Scientific R&D

Copies DNA and loves to drink exquisite green tea

Johannes Wöhrle

Technical R&D

Engineering from micro to macro during working & leisure time

Philipp A. Meyer

Technical R&D

A creative mind for music and science

You are the next!

Awards & PublicaTions


November 2015

Startinsland, Freiburg

1st price (green economy) for BioCopy

July 2015

RSC Emerging Technologies, London

BioCopy (alias immune2day) is within the TOP 10 of health technologies

July 2015

Startinsland, Freiburg

1st price (concept) & 1st price (green economy) for BioCopy

July 2015

CyberOne, Stuttgart

BioCopy is one of the 12 Finalists

June 2015

Elevator Pitch, Stuttgart

1st price in BW for immune2day

May 2015

Black Forest Venture Day, Freiburg

1st price for BioCopy (AptaSWIFT and immune2day)

May 2015

Elevator Pitch, Stuttgart

1st price regional for immune2day

March 2015

Elevator Pitch, Lahr

2nd price regional for AptaSWIFT

Feb 2015

Innovation Price, Freiburg

Price for immune2day

Jan 2015

Science4Life, Berlin

1 x “concept award” for AptaSWIFT

Dec 2014

Science4Life, Frankfurt

1 x “ideas award” for AptaSWIFT

Nov 2014

Startinsland, Freiburg

3rd Place with immune2day


Ideas competition BaWü, Stuttgart

1 x “Development price” to realize a Protein-Copier device


Ideas competition BaWü, Stuttgart

3 x “Evaluation price” with Protein-Kopierer, Gradienten-Stempel and Nanodry




Professionell begleitete Hightech-Ausgründungen als Königsweg.
Dr. Wolfgang Jost, Niko Bausch, Prof. Dr. Bernhard Arnolds,
Best Practice Technologietransfer Baden-Württemberg, Beispiele erfolgreicher Transfersysteme, BIOPRO Baden-Württemberg, 26-33


Low-Volume Label-Free Detection of Molecule-Protein Interactions on Microarrays by Imaging Reflectometric Interferometry
Juergen Burger, Christin Rath, Johannes Woehrle, Philipp A. Meyer, Nessim Ben Ammar, Normann Kilb, Thomas Brandstetter, Florian Pröll, Guenther Proll, Gerald Urban, and Guenter Roth
Journal of Laboratory Automation, DOI: 10.1177/2211068216657512


Semi-contact-writing of polymer molds for prototyping PDMS chips with low surface roughness, sharp edges and locally varying channel heights
L. Gutzweiler, F. Stumpf, L. Tanguy, G. Roth, P. Koltay, R. Zengerle, L. Riegger
2016 J Micromech Microeng, Band: 26, Nummer: 4, Seiten: 45018 – 45027: DOI: 10.1088/0960-1317/26/4/045018




A Peptide-functionalized polymer as a minimal scaffold protein to enhance cluster formation in early T cell signal transduction.
Witsenburg, J. J.; Sinzinger, M. D.; Stoevesandt, O.; Ruttekolk, I. R.; Roth, G.; Adjobo-Hermans, M. J. W.; Brock
Chembiochem; DOI 10.1002/cbic.201402622

Single-cell PCR of genomic DNA enabled by automated single-cell printing for cell isolation
F. Stumpf, J. Schoendube, A. Gross, C. Rath, S. Niekrawietz, P. Koltay, G. Roth;
Biosens Bioelectron; DOI 10.1016/j.bios.2015.03.008


Gründen an Universitäten: Der Königsweg des Technologietransfers.
Niko Bausch, Dr. Wolfgang Jost, und Prof. Dr. Bernhard J. Arnolds,
Special Life Sciences Edition of „Going Public“; 106-107

Protein microarray generation by in situ protein expression from template DNA.
Kilb, N.; Burger, J.; Roth, G
Engineering in Life Sciences ; DOI 10.1002/elsc.201300052

Real-time PCR based detection of a panel of food-borne pathogens on a centrifugal microfluidic "LabDisk" with on-disk quality controls and standards for quantification.
Strohmeier, O.; Marquart, N.; Mark, D.; Roth, G.; Zengerle, R.; Stetten, F. v.
Analytical Methods; DOI 10.1039/C3AY41822G

Human Papillomavirus DNA and Host Gene mRNA Biomarker Detection in a "Micro Total Analysis System" (microTAS) Device to Aid Diagnosis of Cervical Intraepithelial Neoplasia.
Keegan H. and Roth, G. and many others et. al.

A Quantitative Assessment of Costimulation and Phosphatase Activity on Microclusters in Early T Cell Signaling.
Witsenburg, J.J.; Glauner, H. ; Muller, J.P.; Groenewoud, J.M.M.; Roth, G.; Bohmer, FD (Boehmer, Frank-Dietmar)[ 2 ] ; Adjobo-Hermans, M.J.W. ; Brock, R.
PLOS ONE; DOI 10.1371/journal.pone.0079277


Feedstock and Biocatalyst Optimization Starts with an Integrated Genome Data Management Platform.
Bausch, N. et al.
Industrial Biotechnology Journal

Centrifugal gas-phase transition magnetophoresis (GTM)‐a generic method for automation of magnetic bead based assays on the centrifugal microfluidic platform and application to DNA purification.
Strohmeier, O.; Emperle, A.; Roth, G.; Mark, D.; Zengerle, Roland; Stetten, Felix von
Lab on a Chip; DOI 10.1039/c2lc40866j

Multiplex genotyping of KRAS point mutations in tumor cell DNA by allele-specific real-time PCR on a centrifugal microfluidic disk segment.
Strohmeier, O.; Laßmann, S.; Riedel, B.; Mark, D.; Roth, G.; Werner, M. et al.
Microchimica Acta; DOI 10.1007/s00604-013-1099-z

Bubble Jet agent release cartridge for chemical single cell stimulation.
Wangler, N.; Welsche, M.; Blazek, M.; Blessing, M.; Vervliet-Scheebaum, M.; Reski, R., Roth, G. et al.
Biomedical microdevices; DOI 10.1007/s10544-012-9681-4


Mediator probe PCR: a novel approach for detection of real-time PCR based on label-free primary probes and standardized secondary universal fluorogenic reporters.
Faltin, B.; Wadle, S.; Roth, G.; Zengerle, R.; Stetten, F. v.
Clinical chemistry; DOI 10.1373/clinchem.2012

Universal protocol for grafting PCR primers onto various lab-on-a-chip substrates for solid-phase PCR.
Hoffmann, J.; Hin, S.; Stetten, F. v.; Zengerle, R.; Roth, G.
RSC Advances; DOI 10.1039/C2RA01250B

Solid-phase PCR in a picowell array for immobilizing and arraying 100000 PCR products to a microscope slide.
Hoffmann, J.; Trotter, M.; Stetten, F. v.; Zengerle, R.; Roth, G.
Lab on a Chip; DOI 10.1039/c2lc40534b

Construction of a Microstructured Collagen Membrane Mimicking the Papillary Dermis Architecture and Guiding Keratinocyte Morphology and Gene Expression.
Lammers, G.; Roth, G.; Heck, M.; Zengerle, R.; Tjabringa, G. S.; Versteeg, E. M. et al.
Macromolecular bioscience; DOI 10.1002/mabi.201100443

Centrifugo-dynamic inward pumping of liquids on a centrifugal microfluidic platform.
Zehnle, S.; Schwemmer F.; Roth, G.; Stetten, F. v.
Lab on a Chip; DOI 10.1039/c2lc40942a

Nanotechnology-based biosensors and diagnostics: technology push versus industrial/healthcare requirements.
Vashist, S. K.; Venkatesh, A. G.; Mitsakakis, K.; Czilwik, G.; Roth, G.; Stetten, F. v.; Zengerle, R.
BioNanoScience; DOI 10.1007/s12668-012-0047-4


IR thermocycler for centrifugal microfluidic platform with direct wireless temperature measurement system
Burger, J.; Gross, A.; Mark, D., Stetten, F. von; Zengerle, R.; Roth, G., 5 - 9 June 2011,
Beijing, China; IEEE: Piscataway, NJ, 2011.

Controlled counter-flow motion of magnetic bead chains rolling along microchannels.
Karle, M.; Wöhrle, J.; Miwa, J.; Paust, N.; Roth, G.; Zengerle, R.; Stetten, F. v.
Microfluidics and Nanofluidics; DOI 10.1007/s10404-010-0727-8

Protein expression from exogenous mRNA: uptake by receptor-mediated endocytosis and trafficking via the lysosomal pathway.
Lorenz, C.; Fotin-Mleczek, M.; Roth, G.; Becker, C.; Dam, T. C.; Verdurmen, W. P. R. et al.
RNA biology; DOI 10.4161/rna.8.4.15394


Antineuronal antibodies in sporadic late-onset cerebellar ataxia.
Bürk, K.; Wick, M.; Roth, G.; Decker, P.; Voltz, R.
Journal of neurology; DOI 10.1007/s00415-009-5262-8

Microstructuring of polymer films for sensitive genotyping by real-time PCR on a centrifugal microfluidic platform.
Focke, M.; Stumpf, F.; Faltin, B.; Reith, P.; Bamarni, D.; Wadle, S., Roth, G.; et al.
Lab on a Chip; DOI 10.1039/c004954a

Centrifugal microfluidic system for primary amplification and secondary real-time PCR.
Focke, M.; Stumpf, F.; Roth, G.; Zengerle, R.; Stetten, F. v.
Lab on a Chip ; DOI 10.1039/c0lc00161a

Peptide microarrays for the profiling of cytotoxic T-lymphocyte activity using minimum numbers of cells.
Hoff, A.; Bagû, A.-C.; André, T.; Roth, G.; Wiesmüller, K.-H.; Gückel, B.; Brock, R.
Cancer Immunology, Immunotherapy ; DOI 10.1007/s00262-010-0867-4

Continuous microfluidic DNA extraction using phase-transfer magnetophoresis.
Karle, M.; Miwa, J.; Czilwik, G.; Auwärter, V.; Roth, G.; Zengerle, R.; Stetten, F.v.
Lab on a Chip ; DOI 10.1039/c0lc00129e

Reelin signals through apolipoprotein E receptor 2 and Cdc42 to increase growth cone motility and filopodia formation.
Leemhuis, J.; Bouché, E.; Frotscher, M.; Henle, F.; Hein, L.; Herz, J.; Roth, G.; et al.
The Journal of Neuroscience; DOI 10.1523/JNEUROSCI.4036-10.2010

Microfluidic lab-on-a-foil for nucleic acid analysis based on isothermal recombinase polymerase amplification (RPA).
Lutz, S.; Weber, P.; Focke, M.; Faltin, B.; Hoffmann, J.; Müller, C., Roth, G.; et al.
Lab on a Chip; DOI 10.1039/b921140c

Lab-on-a-chip solutions designed for being operated on standard laboratory instruments.
Mark, D.; Focke, M.; Lutz, S.; Burger, J.; Müller, M.; Riegger, L., Roth, G; et al.
Procedia Engineering; DOI 10.1016/j.proeng.2010.09.142

Microfluidic lab-on-a-chip platforms: requirements, characteristics and applications.
Mark, D.; Haeberle, S.; Roth, G.; Stetten, F. v.; Zengerle, R.
Chemical Society Reviews ; DOI 10.1039/B820557B


Physiologische Assays in einem DVD Player am Beispiel der Messung des Hämatokrit.
Burger, J.; Mark, D.; Roth, G.; Müller, C.; Zengerle, R.; Stetten, F. von; Park, Y.

Neurological symptoms in patients with biopsy proven celiac disease.
Bürk, K.; Farecki, M.-L.; Lamprecht, G.; Roth, G.; Decker, P.; Weller, M. et al.
Movement Disorders; DOI 10.1002/mds.22821

Natural Killer Cell Signal Integration Balances Synapse Symmetry and Migration.
Culley, F. J.; Johnson, M.; Evans, J. H.; Kumar, S.; Crilly, R.; Casasbuenas, J., Roth, G.; et al.
PLoS Biol; DOI 10.1371/journal.pbio.1000159

Diffusion-Driven Device for a High-Resolution Dose- Response Profiling of Combination Chemotherapy.
Ganser, A.; Roth, G.; van Galen, J. C; Hilderink, J.; Wammes, J. J. G.; MuĚller, I. et al.
ANALYTICAL CHEMISTRY ; DOI 10.1021/ac900415s

Mikrofluidik-Plattform zur kontinuierlichen Aufreinigung von Biomolekülen.
Karle, M.; Miwa, J.; Haeberle, S.; Roth, G.; Zengerle, R.; Stetten, F. v.
Chemie Ingenieur Technik;

Kontinuierlich arbeitende Mikrofluidik-Plattform zur Aufreinigung von Biomolekülen.
Karle, M.; Miwa, J.; Roth, G.; Haeberle, S.; Zengerle, R.; Stetten, F. v.

Isothermal Polymerase Amplification in a Centrifugal Microfluidic Foil Cartridge.
Lutz, S.; Weber, P.; Focke, M.; Faltin, B.; Roth, G.; Piepenburg, O. et al.
Procedia Chemistry; DOI 10.1016/j.proche.2009.07.132

Lab-on-a-Chip Foundry Service: Schnelle kundenspezifische Implementierung miniaturisierter biochemischer Assays.
Metz, T.; Karle, M.; Preis, T.; Mark, D.; Roth, G.; Müller, C. et al.


Stimulus Dependence of the Action of Small-Molecule Inhibitors in the CD3/CD28 Signalling Network.
Köhler, K.; Ganser, A.; André, T.; Roth, G.; Grosse-Hovest, L.; Jung, G.; Brock, R.
ChemMedChem; DOI 10.1002/cmdc.200800134


Gene Signatures Developed from Patient Tumor Explants Grown in Nude Mice to Predict Tumor Response to 11 Cytotoxic Drugs,
H.-H. Fiebig, J. Schüler, N. Bausch, M. Hofmann, T. Metz, A. Korrat,
Cancer Genomics & Proteomics 4:197 – 210

Ubiquitin Binds to a Short Peptide Segment of Hydrolase UCH-L3: A Study by FCS, RIfS, ITC and NMR.
Roth, G.; Freund, S.; Möhrle, B.; Wöllner, K.; Brünjes, J.; Gauglitz, G. et al.


Diffusion along microfluidic channels.
Heeren, A.; Luo, C. P.; Roth, G.; Ganser, A.; Brock, R.; Wiesmüller, K-H et al.
Microelectronic Engineering; DOI 10.1016/j.mee.2006.01.187

Measuring biomolecular binding events with a compact disc player device.
Lange, S. A.; Roth, G.; Wittemann, S.; Lacoste, T.; Vetter, A.; Grässle, J. et al.
Angewandte Chemie; DOI 10.1002/ange.200501243

Bis 2005

Microsystems for the analysis of cellular signal transduction.
Ganser, A.; Roth, G.; Köhler, K.; André, T.; Heeren, A.; Henschel, W. et al.
NanoBiotechnology; DOI 10.1007/s12030-005-0039-3

Characterisation by 2-D PAGE of host proteins whose synthesis is sustained or stimulated during the course of HSV-1 Infection,
Greco, N. Bausch and Diaz JJ,
Electrophoresis 2000 Jul; 2522-30

Analysis and overexpression in Escherichia coli of a staphylococcal gene encoding seryl-tRNA synthetase,
N. Bausch, L. Seignovert, M. Beaulande, R. Leberman and Härtlein M.,
Biochimica et Biophysica Acta 1397 (1998) 169-174

Softwarekonzepte für eine steuerungsintegrierte Werkzeugüberwachung,
Suwalski, I.; Urban, R.; Burger, J.,
Zeitschrift für wirtschaftlichen Fabrikbetrieb : ZWF 92 (1997), Nr.9, S.436-439, ISSN: 0947-0085


Looking for investors, money welcome


These are our partners of the first hour, which have been on our side even before BioCopy came to life.


BioCopy GmbH
Freiburg, Germany